MMP17 polyclonal (C-term), anti-human, mouse

MMP17 polyclonal (C-term), anti-human, mouse

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In stock
SKU
AC-AP13995b
Catalog Number: AC-AP13995b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33781
Applications: WB, IHC-P
Datasheet

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Background:
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. The protein encoded by this gene isconsidered a member of the membrane-type MMP (MT-MMP) subfamily.However, this protein is unique among the MT-MMP's in that it is aGPI-anchored protein rather than a transmembrane protein. Theprotein activates MMP-2 by cleavage.

Other Names:
Matrix metalloproteinase-17, MMP-17, 3424-, Membrane-type matrix metalloproteinase 4, MT-MMP 4, MTMMP4, Membrane-type-4 matrix metalloproteinase, MT4-MMP, MT4MMP, MMP17, MT4MMP

Target/Specificity:
This MMP17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 432-460 amino acids from the C-terminal region of human MMP17.

Antigen Region:
432-460

Antigen Type: Synthetic Peptide

Gene Name: MMP17
Gene ID: 4326
Primary Accession: Q9ULZ9
NCBI Accession: NP_057239.4
Other Accession: NP_057239.4
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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