MMP2 monoclonal (Ascites), anti-human
€470.00
In stock
SKU
AC-AM1844a
Catalog Number: AC-AM1844a
Size: 100 µl
Isotype: mouse IgG2b,k
Clone Name: 6E3F8
Applications: WB, IHC-P
Datasheet
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Size: 100 µl
Isotype: mouse IgG2b,k
Clone Name: 6E3F8
Applications: WB, IHC-P
Datasheet
Request Information
Background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene.
Other Names:
72 kDa type IV collagenase, 72 kDa gelatinase, Gelatinase A, Matrix metalloproteinase-2, MMP-2, TBE-1, PEX, MMP2, CLG4A
Target/Specificity:
This MMP2 antibody is generated from mouse immunized with MMP2 recombinant protein.
Gene Name: MMP2
Gene ID: 4313
Primary Accession: P08253
NCBI Accession: NP_001121363.1;NP_004521.1
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene.
Other Names:
72 kDa type IV collagenase, 72 kDa gelatinase, Gelatinase A, Matrix metalloproteinase-2, MMP-2, TBE-1, PEX, MMP2, CLG4A
Target/Specificity:
This MMP2 antibody is generated from mouse immunized with MMP2 recombinant protein.
Gene Name: MMP2
Gene ID: 4313
Primary Accession: P08253
NCBI Accession: NP_001121363.1;NP_004521.1
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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