MMP2 polyclonal, anti-human, mouse, rat

Background:
Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways.

Synonyms: CLG4, CLG4A, MMP-2, MMP-II, MONA, TBE-1

Cellular Location: Cytoplasm Membrane Mitochondrion Nucleus Secreted extracellular matrix extracellular space

Immunogen:
A synthetic peptide of human MMP2

Gene Symbol: MMP2

Gene ID: 4313

Swiss prot: P08253

Calculated MW: 72kDa

Recommended dilution:
IHC 1:50

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.