MMP2 Polyclonal Antibody

Background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response.

Research Area: Cardiovascular, Cancer, Cell Biology, Metabolism

Synonyms:
72 kDa gelatinase, CLG4, CLG4A, Collagenase Type 4 alpha, Gelatinase A, Matrix Metalloproteinase 2, MMP 2, MONA, Neutrophil gelatinase, PEX, TBE 1

Immunogen: Recombinant Rat 72 kDa type IV collagenase protein

Swissprot: P33436
Gene ID: 81686

Calculated MW: 74 kDa
Observed MW: 74 kDa

Purification Method: Antigen Affinity Purification

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3

Concentration: 0.5 mg/mL
Dilution: WB 1:500-1:2000 IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.