MMP20 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13895b
Background:
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. The protein encoded by this genedegrades amelogenin, the major protein component of dental enamelmatrix, and so the protein is thought to play a role in toothenamel formation. A mutation in this gene, which alters the normalsplice pattern and results in premature termination of the encodedprotein, has been associated with amelogenesis imperfecta. Thisgene is part of a cluster of MMP genes that localizes to chromosome11q22.3.
Other Names:
Matrix metalloproteinase-20, MMP-20, 3424-, Enamel metalloproteinase, Enamelysin, MMP20
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13895b was selected from the C-term region of MMP20. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MMP20
Gene ID: 9313
Primary Accession: O60882
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. The protein encoded by this genedegrades amelogenin, the major protein component of dental enamelmatrix, and so the protein is thought to play a role in toothenamel formation. A mutation in this gene, which alters the normalsplice pattern and results in premature termination of the encodedprotein, has been associated with amelogenesis imperfecta. Thisgene is part of a cluster of MMP genes that localizes to chromosome11q22.3.
Other Names:
Matrix metalloproteinase-20, MMP-20, 3424-, Enamel metalloproteinase, Enamelysin, MMP20
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13895b was selected from the C-term region of MMP20. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MMP20
Gene ID: 9313
Primary Accession: O60882
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
| Is Featured? | No |
|---|
Write Your Own Review