MMP20 polyclonal (C-term), anti-human
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In stock
SKU
AC-AP13895b
Catalog Number: AC-AP13895b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34032
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34032
Applications: WB
Datasheet
Request Information
Background:
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. The protein encoded by this genedegrades amelogenin, the major protein component of dental enamelmatrix, and so the protein is thought to play a role in toothenamel formation. A mutation in this gene, which alters the normalsplice pattern and results in premature termination of the encodedprotein, has been associated with amelogenesis imperfecta. Thisgene is part of a cluster of MMP genes that localizes to chromosome11q22.3.
Other Names:
Matrix metalloproteinase-20, MMP-20, 3424-, Enamel metalloproteinase, Enamelysin, MMP20
Target/Specificity:
This MMP20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-428 amino acids from the C-terminal region of human MMP20.
Antigen Region:
399-428
Antigen Type: Synthetic Peptide
Gene Name: MMP20
Gene ID: 9313
Primary Accession: O60882
NCBI Accession: NP_004762.2
Other Accession: O18767; NP_004762.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. The protein encoded by this genedegrades amelogenin, the major protein component of dental enamelmatrix, and so the protein is thought to play a role in toothenamel formation. A mutation in this gene, which alters the normalsplice pattern and results in premature termination of the encodedprotein, has been associated with amelogenesis imperfecta. Thisgene is part of a cluster of MMP genes that localizes to chromosome11q22.3.
Other Names:
Matrix metalloproteinase-20, MMP-20, 3424-, Enamel metalloproteinase, Enamelysin, MMP20
Target/Specificity:
This MMP20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-428 amino acids from the C-terminal region of human MMP20.
Antigen Region:
399-428
Antigen Type: Synthetic Peptide
Gene Name: MMP20
Gene ID: 9313
Primary Accession: O60882
NCBI Accession: NP_004762.2
Other Accession: O18767; NP_004762.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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