MMP26 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP6207a
Background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP26 may hydrolyze collagen type IV, fibronectin, fibrinogen, beta-casein, type I gelatin and alpha-1 proteinase inhibitor. It is also able to activates progelatinase B. MMP26 is expressed specifically in uterus and placenta. Is also widely expressed in malignant tumors from different sources as well as in diverse tumor cell lines.
Other Names:
Matrix metalloproteinase-26, MMP-26, 3424-, Endometase, Matrilysin-2, MMP26
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6207a was selected from the N-term region of human MMP26 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MMP26
Gene ID: 56547
Primary Accession: Q9NRE1
Other Accession: NP_068573
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP26 may hydrolyze collagen type IV, fibronectin, fibrinogen, beta-casein, type I gelatin and alpha-1 proteinase inhibitor. It is also able to activates progelatinase B. MMP26 is expressed specifically in uterus and placenta. Is also widely expressed in malignant tumors from different sources as well as in diverse tumor cell lines.
Other Names:
Matrix metalloproteinase-26, MMP-26, 3424-, Endometase, Matrilysin-2, MMP26
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6207a was selected from the N-term region of human MMP26 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MMP26
Gene ID: 56547
Primary Accession: Q9NRE1
Other Accession: NP_068573
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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