MMP27 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP6208a
Background:
Matrix Metalloproteases (MMPs) are zinc-dependent endopeptidases that break down the extracellular matrix, and thus play important roles in many physiological processes including embryonic development, wound healing, reproduction, tissue remodeling, arthritis, cancer and cardiovascular disease. Although most MMPs are secreted, the membrane-type MMPs (MT-MMPs) are anchored to the cell membrane by a transmembrane and intracytoplasmic domain. MMP activities are regulated at several levels, including cleavage of proenzyme forms and suppression via tissue inhibitors of metalloproteinases (TIMPs). The 513 amino acid human MMP27 protein is located primarily in extracellular spaces in the extracellular matrix, and maps to chromosome 11q24.
Other Names:
Matrix metalloproteinase-27, MMP-27, 3424-, MMP27
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6208a was selected from the C-term region of human MMP27 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MMP27
Gene ID: 64066
Primary Accession: Q9H306
Other Accession: MM27_HUMAN
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Matrix Metalloproteases (MMPs) are zinc-dependent endopeptidases that break down the extracellular matrix, and thus play important roles in many physiological processes including embryonic development, wound healing, reproduction, tissue remodeling, arthritis, cancer and cardiovascular disease. Although most MMPs are secreted, the membrane-type MMPs (MT-MMPs) are anchored to the cell membrane by a transmembrane and intracytoplasmic domain. MMP activities are regulated at several levels, including cleavage of proenzyme forms and suppression via tissue inhibitors of metalloproteinases (TIMPs). The 513 amino acid human MMP27 protein is located primarily in extracellular spaces in the extracellular matrix, and maps to chromosome 11q24.
Other Names:
Matrix metalloproteinase-27, MMP-27, 3424-, MMP27
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6208a was selected from the C-term region of human MMP27 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MMP27
Gene ID: 64066
Primary Accession: Q9H306
Other Accession: MM27_HUMAN
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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