MMP3 Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13536a
Background:
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. This gene encodes an enzyme whichdegrades fibronectin, laminin, collagens III, IV, IX, and X, andcartilage proteoglycans. The enzyme is thought to be involved inwound repair, progression of atherosclerosis, and tumor initiation.The gene is part of a cluster of MMP genes which localize tochromosome 11q22.3.
Other Names:
Stromelysin-1, SL-1, Matrix metalloproteinase-3, MMP-3, Transin-1, MMP3, STMY1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13536a was selected from the N-term region of MMP3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MMP3
Gene ID: 4314
Primary Accession: P08254
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. This gene encodes an enzyme whichdegrades fibronectin, laminin, collagens III, IV, IX, and X, andcartilage proteoglycans. The enzyme is thought to be involved inwound repair, progression of atherosclerosis, and tumor initiation.The gene is part of a cluster of MMP genes which localize tochromosome 11q22.3.
Other Names:
Stromelysin-1, SL-1, Matrix metalloproteinase-3, MMP-3, Transin-1, MMP3, STMY1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13536a was selected from the N-term region of MMP3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MMP3
Gene ID: 4314
Primary Accession: P08254
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
| Is Featured? | No |
|---|
Write Your Own Review