MMP3 polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP13536a
Catalog Number: AC-AP13536a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33616
Applications: WB, IF, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33616
Applications: WB, IF, IHC-P
Datasheet
Request Information
Background:
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. This gene encodes an enzyme whichdegrades fibronectin, laminin, collagens III, IV, IX, and X, andcartilage proteoglycans. The enzyme is thought to be involved inwound repair, progression of atherosclerosis, and tumor initiation.The gene is part of a cluster of MMP genes which localize tochromosome 11q22.3.
Other Names:
Stromelysin-1, SL-1, Matrix metalloproteinase-3, MMP-3, Transin-1, MMP3, STMY1
Target/Specificity:
This MMP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of human MMP3.
Antigen Region:
30-59
Antigen Type: Synthetic Peptide
Gene Name: MMP3
Gene ID: 4314
Primary Accession: P08254
NCBI Accession: NP_002413.1
Other Accession: NP_002413.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. This gene encodes an enzyme whichdegrades fibronectin, laminin, collagens III, IV, IX, and X, andcartilage proteoglycans. The enzyme is thought to be involved inwound repair, progression of atherosclerosis, and tumor initiation.The gene is part of a cluster of MMP genes which localize tochromosome 11q22.3.
Other Names:
Stromelysin-1, SL-1, Matrix metalloproteinase-3, MMP-3, Transin-1, MMP3, STMY1
Target/Specificity:
This MMP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of human MMP3.
Antigen Region:
30-59
Antigen Type: Synthetic Peptide
Gene Name: MMP3
Gene ID: 4314
Primary Accession: P08254
NCBI Accession: NP_002413.1
Other Accession: NP_002413.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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