MMP7 polyclonal, anti-mouse, rat

Quantity: 100 µg

Background:
MMP7, matrix metalloproteinase-7, is an enzyme that in humans is encoded by the MMP7 gene. The MMP7 protein has 267 amino acids and is significantly shorter than stromelysin or collagenase. By Southern and PCR analysis of 2 different panels of somatic cell hybrids and by isotopic in situ hybridization, the MMP7 gene is mapped to 11q21-q22. It is a member of matrix metalloproteinase family. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa.

Description:
Rabbit IgG polyclonal antibody for Matrilysin (MMP7) detection. Tested with WB, IHC-P in Mouse, Rat.

Synonyms:
Matrilysin antibody, Matrilysin uterine antibody, Matrin antibody, Matrix Metalloproteinase 7 antibody, Matrix metalloproteinase-7 antibody, MMP 7 antibody, MMP-7 antibody, MMP7 antibody, MMP7_HUMAN antibody, MPSL1 antibody, PUMP 1 antibody, Pump 1 protease antibody, Pump-1 protease antibody, PUMP1 antibody, Uterine Matrilysin antibody, Uterine metalloproteinase antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of mouse MMP7(236-252aa YQRDYSEDFSLTKDDIA), different from the related rat sequence by two amino acids.A synthetic peptide corresponding to a sequence at the C-terminus of mouse MMP7(236-252aa YQRDYSEDFSLTKDDIA), different from the related rat sequence by two amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.