MMP7 Polyclonal Antibody

Background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Research Area: Cancer, Cell Biology, Cardiovascular, Signal Transduction

Synonyms:
Matrilysin, Matrin, Matrix Metalloproteinase 7, Matrix metalloproteinase-7, MMP 7, MMP-7, MMP7, MMP7, MPSL1, PUMP 1, Pump 1 protease, Pump-1 protease, PUMP1, Uterine matrilysin, Uterine metalloproteinase

Immunogen: Recombinant protein of human MMP7

Swissprot: P09237
Gene Accession: BC003635

Calculated MW: 30 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-8832/sc-26674/sc-30071