MMP8 polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP13723a
Catalog Number: AC-AP13723a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33692
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33692
Applications: WB
Datasheet
Request Information
Background:
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. However, the enzyme encoded by thisgene is stored in secondary granules within neutrophils and isactivated by autolytic cleavage. Its function is degradation oftype I, II and III collagens. The gene is part of a cluster of MMPgenes which localize to chromosome 11q22.3.
Other Names:
Neutrophil collagenase, Matrix metalloproteinase-8, MMP-8, PMNL collagenase, PMNL-CL, MMP8, CLG1
Target/Specificity:
This MMP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-84 amino acids from the N-terminal region of human MMP8.
Antigen Region:
56-84
Antigen Type: Synthetic Peptide
Gene Name: MMP8
Gene ID: 4317
Primary Accession: P22894
NCBI Accession: NP_002415.1
Other Accession: NP_002415.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. However, the enzyme encoded by thisgene is stored in secondary granules within neutrophils and isactivated by autolytic cleavage. Its function is degradation oftype I, II and III collagens. The gene is part of a cluster of MMPgenes which localize to chromosome 11q22.3.
Other Names:
Neutrophil collagenase, Matrix metalloproteinase-8, MMP-8, PMNL collagenase, PMNL-CL, MMP8, CLG1
Target/Specificity:
This MMP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-84 amino acids from the N-terminal region of human MMP8.
Antigen Region:
56-84
Antigen Type: Synthetic Peptide
Gene Name: MMP8
Gene ID: 4317
Primary Accession: P22894
NCBI Accession: NP_002415.1
Other Accession: NP_002415.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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