MMP9 monoclonal, anti-human

Background:
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. The enzyme encoded by this genedegrades type IV and V collagens. Studies in rhesus monkeys suggestthat the enzyme is involved in IL-8-induced mobilization ofhematopoietic progenitor cells from bone marrow, and murine studiessuggest a role in tumor-associated tissue remodeling. [provided byRefSeq].

Other Names:
Matrix metalloproteinase-9, MMP-9, 92 kDa gelatinase, 92 kDa type IV collagenase, Gelatinase B, GELB, 67 kDa matrix metalloproteinase-9, 82 kDa matrix metalloproteinase-9, MMP9, CLG4B

Target/Specificity:
Purified His-tagged MMP9 protein(Fragment) was used to produced this monoclonal antibody.

Antigen Type: Recombinant Protein

Gene Name: MMP9
Gene ID: 4318
Primary Accession: P14780
NCBI Accession: NP_004985.2
Other Accession: NP_004985.2
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.