MMP9 polyclonal, anti-human, mouse, rat

Background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.

Synonyms: CLG4B, GELB, MANDP2, MMP-9

Cellular Location: Secreted extracellular matrix extracellular space

Immunogen:
A synthetic peptide of human MMP9

Gene Symbol: MMP9

Gene ID: 4318

Swiss prot: P14780

Calculated MW: 78kDa

Recommended dilution:
WB 1:500-2000, IHC 1:100-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.