MMP9 polyclonal (C-term), anti-human

MMP9 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP16581b
Catalog Number: AC-AP16581b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33612
Applications: WB
Datasheet

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Background:
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. The enzyme encoded by this genedegrades type IV and V collagens. Studies in rhesus monkeys suggestthat the enzyme is involved in IL-8-induced mobilization ofhematopoietic progenitor cells from bone marrow, and murine studiessuggest a role in tumor-associated tissue remodeling. [provided byRefSeq].

Other Names:
Matrix metalloproteinase-9, MMP-9, 92 kDa gelatinase, 92 kDa type IV collagenase, Gelatinase B, GELB, 67 kDa matrix metalloproteinase-9, 82 kDa matrix metalloproteinase-9, MMP9, CLG4B

Target/Specificity:
This MMP9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 549-578 amino acids from the C-terminal region of human MMP9.

Antigen Region:
549-578

Antigen Type: Synthetic Peptide

Gene Name: MMP9
Gene ID: 4318
Primary Accession: P14780
NCBI Accession: NP_004985.2
Other Accession: NP_004985.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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