MMS2 polyclonal, anti-human, mouse, rat
€469.00
In stock
SKU
251960
Protein Family: Enzymes, Ubiquitins
Pathway and Disease: Signaling Molecules and Interaction, Replication and Repair
Description:
Ubiquitin-conjugating enzyme E2 variant 2 (MMS2) catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'Ia a heterodimer that This type of poly-ubiquitination does not lead to protein degradation by the proteasome. MMS2 has no ubiquitin ligase activity on its own. MMS2 mediates transcriptional activation of target genes and plays a role in the control of progress through the cell cycle and differentiation. MMS2 plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
Alternate Names: Ubiquitin-conjugating enzyme E2 variant 2, MMS2 homolog, Enterocyte differentiation-associated factor 1, EDAF-1, Enterocyte differentiation-promoting factor 1, EDPF-1, Vitamin D3-inducible protein, DDVit 1, UBE2V2, MMS2, UEV2
Application Notes: E: 1:1,000-1:50,000; WB: 1:100-1:500
Accession No.: Q15819
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human MMS2.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.5% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction, Replication and Repair
Description:
Ubiquitin-conjugating enzyme E2 variant 2 (MMS2) catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'Ia a heterodimer that This type of poly-ubiquitination does not lead to protein degradation by the proteasome. MMS2 has no ubiquitin ligase activity on its own. MMS2 mediates transcriptional activation of target genes and plays a role in the control of progress through the cell cycle and differentiation. MMS2 plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
Alternate Names: Ubiquitin-conjugating enzyme E2 variant 2, MMS2 homolog, Enterocyte differentiation-associated factor 1, EDAF-1, Enterocyte differentiation-promoting factor 1, EDPF-1, Vitamin D3-inducible protein, DDVit 1, UBE2V2, MMS2, UEV2
Application Notes: E: 1:1,000-1:50,000; WB: 1:100-1:500
Accession No.: Q15819
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human MMS2.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.5% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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