MOB1A Polyclonal Antibody

Background:
MOB1 was first identified in yeast as a protein that binds to Mps with essential roles in the completion of mitosis and the maintenance of ploidy. ItsDrosophilaand mammalian homologs, Mats and MOB1, respectively, are involved in the Hippo signaling tumor suppressor pathway, which plays a critical role in organ size regulation and which has been implicated in cancer development . There are two MOB1 proteins in humans, MOB1α and MOB1β, that are encoded by two different genes but which have greater than 95% amino acid sequence identity.

Research Area: Cancer, Signal Transduction

Synonyms:
B1, Mps One Binder kinase activator like 1B (yeast), C2orf6, Chromosome 2 open reading frame 6, FLJ10788, FLJ11595, MATS1, MOB kinase activator 1A, MOB1, Mob1 alpha, Mob1 homolog 1B, MOB1 Mps One Binder homolog A, MOB1 Mps One Binder kinase activator like 1B, Mob1A, MOB4B, Mob4B protein, MOBK1B, Mobkl1b, MOL1B, Mps one binder kinase activator like 1B, Mps one binder kinase activator-like 1B, Protein Mob4B

Immunogen: Fusion protein of human MOB1A

Swissprot: Q9H8S9
Gene Accession: BC003398

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.84 mg/mL
Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.