Moesin polyclonal, anti-human, mouse, rat

Background:
Ezrin, Moesin and Radixin belong to a family of highly homologous Actin-associated proteins that are localized just beneath the plasma membrane. These proteins are believed to be involved in the mediation of interactions between cytoskeletal and membrane proteins. Ezrin serves as a major cytoplasmic substrate of various protein-tyrosine kinases, including the epidermal growth factor receptor. Ezrin has also been identified as a cAMP-dependent protein kinase (A-kinase) anchoring protein and designated AKAP78. Moesin and Radixin share more than 70% homology with Ezrin and are co-expressed within various cell types. Despite the high degree of homology, the three proteins exhibit a distinct receptor-specific pattern of phosphorylation.

Alternative Name:
MSN, Epididymis luminal protein 70, HEL70, Membrane organizing extension spike protein, Membrane-organizing extension spike protein, MOES, Moesin, Moesin/anaplastic lymphoma kinase fusion protein, Msn, MSN/ALK fusion,

Application Dilution:
WB:1:1,000-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Specificity: Moesin polyclonal antibody detects endogenous levels of Moesin protein.

Immunogen:
recombinant protein

MW: 68 kDa

Swiss-Prot: P26038(Human) P26041(Mouse) O35763(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.