MOF rabbit polyclonal, anti-human, mouse, rat

Backgroud: This gene encodes a member of the MYST histone acetylase protein family. The encoded protein has a characteristic MYST domain containing an acetyl-CoA-binding site, a chromodomain typical of proteins which bind histones, and a C2HC-type zinc finger. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012],catalytic activity:Acetyl-CoA + histone = CoA + acetylhistone.,function:Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM.,similarity:Belongs to the MYST (SAS/MOZ) family.,similarity:Contains 1 C2HC-type zinc finger.,similarity:Contains 1 chromo domain.,subunit:Component of a multisubunit histone acetyltransferase complex (MSL) at least composed of the MOF/MYST1, MSL1/hampin, MSL2L1 and MSL3L1. Interacts with the chromodomain of MORF4L1/MRG15. Interacts with ATM through the chromodomain.,

Synonyms: KAT8, MOF, MYST1, PP7073, Histone acetyltransferase KAT8, Lysine acetyltransferase 8, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1, MYST-1, hMOF

Gene Name: KAT8

Gene ID: 84148

SwissProt ID: Q9H7Z6

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.