MOG [35-55] Peptide (Rat)
€183.00
In stock
SKU
350275
Protein Family: Cellular Antigens, Chaperones and Folding Catalysts
Pathway and Disease: Cell Communication, Nervous and Sensory Systems, Neurodegenerative Disorders
Alternate Names: Myelin-oligodendrocyte glycoprotein; Mog; MOG (35-55)
Accession No.: Q63345
Description:
Myelin-oligodendrocyte glycoprotein (MOG) is a minor component of the myelin sheath. MOG is also a CNS-specific autoantigen for primary demyelination in multiple sclerosis. The developmentally late expression of MOG correlates with the later stages of myelogenesis, suggesting that MOG has a role in the completion, compaction and maintenance of myelin. MOG has many isoforms that can form homo- and heterodimers. It has been shown that the MOG [35-55] peptide induced anti-MOG (35-55) autoantibody production in C57BL/6 mice with 100% incident (10/10), providing quantitative support for the suitability of the MOG peptide for in vivo anti-MOG (35-55) autoantibody study.
Format:
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
MW: 2582 g/mol
Sequence:
Rat: H-Met-Glu-Val-Gly-Trp-Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys-OH or H-MEVGWYRSPFSRVVHLYRNGK-OH
Composition:
C118H177N35O29S1
Purity:
> 95% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Pathway and Disease: Cell Communication, Nervous and Sensory Systems, Neurodegenerative Disorders
Alternate Names: Myelin-oligodendrocyte glycoprotein; Mog; MOG (35-55)
Accession No.: Q63345
Description:
Myelin-oligodendrocyte glycoprotein (MOG) is a minor component of the myelin sheath. MOG is also a CNS-specific autoantigen for primary demyelination in multiple sclerosis. The developmentally late expression of MOG correlates with the later stages of myelogenesis, suggesting that MOG has a role in the completion, compaction and maintenance of myelin. MOG has many isoforms that can form homo- and heterodimers. It has been shown that the MOG [35-55] peptide induced anti-MOG (35-55) autoantibody production in C57BL/6 mice with 100% incident (10/10), providing quantitative support for the suitability of the MOG peptide for in vivo anti-MOG (35-55) autoantibody study.
Format:
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
MW: 2582 g/mol
Sequence:
Rat: H-Met-Glu-Val-Gly-Trp-Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys-OH or H-MEVGWYRSPFSRVVHLYRNGK-OH
Composition:
C118H177N35O29S1
Purity:
> 95% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
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