MORC2 Polyclonal Antibody

Background:
The CW domain is a structural module found in many vertebrate, parasitic and plant proteins. It consists of a mononuclear four-cysteine zinc-finger domain that plays a role in DNA binding, chromatin methylation and early embryonic development. ZCWCC1 (zinc finger CW-type coiled-coil domain protein 1), also known as MORC2 (MORC family CW-type zinc finger protein 2) or ZCW3, is a 1, 032 amino acid protein that contains one CW-type zinc finger domain. ZCWCC1 is located on chromosome 22 and is ubiquitously expressed with highest expression in pancreas, smooth muscle and testis. Expression of ZCWCC1 is upregulated in hypoxia, a pathological condition characterized by an inadequate supply of oxygen in the blood.

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
AC004542.C22.1., CW type with coiled coil domain 1, KIAA0852, MORC family CW type zinc finger 2, MORC family CW-type zinc finger protein 2, MORC2, MORC2, ZCW3, ZCWCC1, Zinc finger, Zinc finger CW type coiled coil domain protein 1, Zinc finger CW type with coiled coil domain 1, Zinc finger CW-type coiled-coil domain protein 1, Zing finger CW type 3

Immunogen: Fusion protein of human MORC2

Swissprot: Q9Y6X9
Gene Accession: BC019257

Calculated MW: 118 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.5 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.