MORF4L2 polyclonal, anti-human
€388.00
In stock
SKU
BS70818
Background:
The members of the mortality factor family include mortality factor 4 (MORF4), mortality factor 4 like 1 (MORF4L1), also known as MORF4-related gene 15 (MRG15), and mortality factor 4 like 2 (MORF4L2), also known as MORF-4 related gene X (MRGX). The human MORF4 gene maps to chromosome 4q34.1. MORF4 induces a senescent-like phenotype in complementation group B immortal cell lines. The genes encoding MORF4L1 and MORF4L2 map to chromosomes 15q25.1 and Xq22.2, respectively. MORF4, MORF4L1 and MORF4L2 each contain a C-terminal leucine zipper. An association between MORF4L1, Rb (retinoblastoma tumor suppressor) and PAM14 (protein associated with MORF4L1) suggests a role for MORF4L1 in transcription regulation. MORF4L1 also associates with the histone acetyl transferase MOF.
Alternative Name:
MRGX, MORFL2,
Application Dilution: IF: 1:50 - 1:100
Specificity: MORF4L2 polyclonal antibody detects endogenous levels of MORF4L2 protein.
Immunogen:
Recombinant protein of human MORF4L2.
MW: ~ 32 kDa
Swis Prot.: Q15014
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The members of the mortality factor family include mortality factor 4 (MORF4), mortality factor 4 like 1 (MORF4L1), also known as MORF4-related gene 15 (MRG15), and mortality factor 4 like 2 (MORF4L2), also known as MORF-4 related gene X (MRGX). The human MORF4 gene maps to chromosome 4q34.1. MORF4 induces a senescent-like phenotype in complementation group B immortal cell lines. The genes encoding MORF4L1 and MORF4L2 map to chromosomes 15q25.1 and Xq22.2, respectively. MORF4, MORF4L1 and MORF4L2 each contain a C-terminal leucine zipper. An association between MORF4L1, Rb (retinoblastoma tumor suppressor) and PAM14 (protein associated with MORF4L1) suggests a role for MORF4L1 in transcription regulation. MORF4L1 also associates with the histone acetyl transferase MOF.
Alternative Name:
MRGX, MORFL2,
Application Dilution: IF: 1:50 - 1:100
Specificity: MORF4L2 polyclonal antibody detects endogenous levels of MORF4L2 protein.
Immunogen:
Recombinant protein of human MORF4L2.
MW: ~ 32 kDa
Swis Prot.: Q15014
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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