Mouse Akt1 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP14703a
Background:
This gene encodes the founding member of the Aktserine-threonine protein kinase gene family that also includes Akt2and Akt3. This kinase is a major downstream effector of thephosphatidylinositol 3-kinase (PI3K) pathway that mediates theeffects of various growth factors such as platelet-derived growthfactor (PDGF), epidermal growth factor (EGF), insulin andinsulin-like growth factor I (IGF-I). It is activated throughrecruitment to cellular membranes by PI3K lipid products and byphosphorylation by 3-phosphoinositide dependent kinase-1. It thenfurther phosphorylates different downstream proteins in response tovarious extracellular signals and thus plays a pivotal role inmediating a variety of cellular processes, such as glucosemetabolism, glycogen biosynthesis, protein synthesis and turn over,inflammatory response, cell survival (anti-apoptosis) anddevelopment. Alternatively spliced transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
Other Names:
RAC-alpha serine/threonine-protein kinase, AKT1 kinase, Protein kinase B, PKB, Protein kinase B alpha, PKB alpha, Proto-oncogene c-Akt, RAC-PK-alpha, Thymoma viral proto-oncogene, Akt1, Akt, Rac
Gene Name: Akt1
Gene ID: 11651
Primary Accession: P31750
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes the founding member of the Aktserine-threonine protein kinase gene family that also includes Akt2and Akt3. This kinase is a major downstream effector of thephosphatidylinositol 3-kinase (PI3K) pathway that mediates theeffects of various growth factors such as platelet-derived growthfactor (PDGF), epidermal growth factor (EGF), insulin andinsulin-like growth factor I (IGF-I). It is activated throughrecruitment to cellular membranes by PI3K lipid products and byphosphorylation by 3-phosphoinositide dependent kinase-1. It thenfurther phosphorylates different downstream proteins in response tovarious extracellular signals and thus plays a pivotal role inmediating a variety of cellular processes, such as glucosemetabolism, glycogen biosynthesis, protein synthesis and turn over,inflammatory response, cell survival (anti-apoptosis) anddevelopment. Alternatively spliced transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
Other Names:
RAC-alpha serine/threonine-protein kinase, AKT1 kinase, Protein kinase B, PKB, Protein kinase B alpha, PKB alpha, Proto-oncogene c-Akt, RAC-PK-alpha, Thymoma viral proto-oncogene, Akt1, Akt, Rac
Gene Name: Akt1
Gene ID: 11651
Primary Accession: P31750
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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