mouse BAD polyclonal (Center S112/S111/Y113), anti-mouse
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In stock
SKU
AC-AP18695c
Catalog Number: AC-AP18695c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB39400
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB39400
Applications: WB
Datasheet
Request Information
Background:
BAD promotes cell death. It successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Other Names:
Bcl2-associated agonist of cell death, BAD, Bcl-2-binding component 6, Bcl-xL/Bcl-2-associated death promoter, Bcl2 antagonist of cell death, Bad, Bbc6
Target/Specificity:
This mouse BAD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-118 amino acids from the Central region of mouse BAD.
Antigen Region:
90-118
Antigen Type: Synthetic Peptide
Gene Name: Bad
Gene ID: 12015
Primary Accession: Q61337
NCBI Accession: NP_031548.1
Other Accession: O35147; NP_031548.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
BAD promotes cell death. It successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Other Names:
Bcl2-associated agonist of cell death, BAD, Bcl-2-binding component 6, Bcl-xL/Bcl-2-associated death promoter, Bcl2 antagonist of cell death, Bad, Bbc6
Target/Specificity:
This mouse BAD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-118 amino acids from the Central region of mouse BAD.
Antigen Region:
90-118
Antigen Type: Synthetic Peptide
Gene Name: Bad
Gene ID: 12015
Primary Accession: Q61337
NCBI Accession: NP_031548.1
Other Accession: O35147; NP_031548.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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