Mouse Casc5 polyclonal (C-term), anti-mouse
€0.00
In stock
SKU
AC-AP19227b
Catalog Number: AC-AP19227b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB40173
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB40173
Applications: WB
Datasheet
Request Information
Background:
Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Directly links spindle checkpoint proteins BUB1 and BUB1B to kinetochores. Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. Acts in coordination with CENPK to recruit the NDC80 complex to the outer kinetochore (By similarity).
Other Names:
Protein CASC5, Cancer susceptibility candidate gene 5 protein homolog, Kinetochore-null protein 1, Casc5, Knl1
Target/Specificity:
This Mouse Casc5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1557-1583 amino acids from the C-terminal region of mouse Casc5.
Antigen Region:
1557-1583
Antigen Type: Synthetic Peptide
Gene Name: Knl1 {ECO:0000312|MGI:MGI:1923714}
Primary Accession: Q66JQ7
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Directly links spindle checkpoint proteins BUB1 and BUB1B to kinetochores. Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. Acts in coordination with CENPK to recruit the NDC80 complex to the outer kinetochore (By similarity).
Other Names:
Protein CASC5, Cancer susceptibility candidate gene 5 protein homolog, Kinetochore-null protein 1, Casc5, Knl1
Target/Specificity:
This Mouse Casc5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1557-1583 amino acids from the C-terminal region of mouse Casc5.
Antigen Region:
1557-1583
Antigen Type: Synthetic Peptide
Gene Name: Knl1 {ECO:0000312|MGI:MGI:1923714}
Primary Accession: Q66JQ7
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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