Mouse Chek2 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP14706b
Background:
Chek2 regulates cell cycle checkpoints and apoptosis in response to DNA damage, particularly to DNA double-strand breaks. Inhibits CDC25C phosphatase by phosphorylation, preventing the entry into mitosis. May also play a role in meiosis. Regulates the TP53 tumor suppressor through phosphorylation at 'Thr-20' and 'Ser-23'.
Other Names:
Serine/threonine-protein kinase Chk2, CHK2 checkpoint homolog, Checkpoint kinase 2, Chek2, Chk2, Rad53
Gene Name: Chek2 {ECO:0000312|MGI:MGI:1355321}
Gene ID: 50883
Primary Accession: Q9Z265
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Chek2 regulates cell cycle checkpoints and apoptosis in response to DNA damage, particularly to DNA double-strand breaks. Inhibits CDC25C phosphatase by phosphorylation, preventing the entry into mitosis. May also play a role in meiosis. Regulates the TP53 tumor suppressor through phosphorylation at 'Thr-20' and 'Ser-23'.
Other Names:
Serine/threonine-protein kinase Chk2, CHK2 checkpoint homolog, Checkpoint kinase 2, Chek2, Chk2, Rad53
Gene Name: Chek2 {ECO:0000312|MGI:MGI:1355321}
Gene ID: 50883
Primary Accession: Q9Z265
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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