Mouse Derl2 polyclonal (C-term), anti-mouse
€0.00
In stock
SKU
AC-AP19315b
Catalog Number: AC-AP19315b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB40190
Applications: WB
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB40190
Applications: WB
Datasheet
Request Information
Background:
Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate (By similarity).
Other Names:
Derlin-2, Degradation in endoplasmic reticulum protein 2, Der1-like protein 2, F-LANa, Derl2, Der2, Flana
Target/Specificity:
This Mouse Derl2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-219 amino acids from the C-terminal region of mouse Derl2.
Antigen Region:
191-219
Antigen Type: Synthetic Peptide
Gene Name: Derl2 {ECO:0000312|MGI:MGI:2151483}
Gene ID: 116891
Primary Accession: Q8BNI4
NCBI Accession: NP_291040.1
Other Accession: NP_291040.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate (By similarity).
Other Names:
Derlin-2, Degradation in endoplasmic reticulum protein 2, Der1-like protein 2, F-LANa, Derl2, Der2, Flana
Target/Specificity:
This Mouse Derl2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-219 amino acids from the C-terminal region of mouse Derl2.
Antigen Region:
191-219
Antigen Type: Synthetic Peptide
Gene Name: Derl2 {ECO:0000312|MGI:MGI:2151483}
Gene ID: 116891
Primary Accession: Q8BNI4
NCBI Accession: NP_291040.1
Other Accession: NP_291040.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
|---|
Write Your Own Review