Mouse Dnmt3L Antibody Blocking Peptide
€363.00
In stock
SKU
AC-BP1062a
Background:
mDnmt3L (DNA methyltransferase 3L) does not appear to be catalytically active due to loss of the critical active site residues. It may function not directly as a DNA methyltransferase but rather as a regulator of methylation at imprinted loci. It is required specifically for the establishment of genomic imprints but is dispensable for their propagation. It is essential for the de novo methylation of single-copy DNA sequences. The protein is well-express in testis, thymus, ovary, and heart. mDnmt3L, which belongs to the 5-cytosine methyltransferase family, contains 1 ADD-type zinc finger.
Other Names:
DNA (cytosine-5)-methyltransferase 3-like, Dnmt3l
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1062a was selected from the region of human Mouse Dnmt3L. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: Dnmt3l
Gene ID: 54427
Primary Accession: Q9CWR8
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
mDnmt3L (DNA methyltransferase 3L) does not appear to be catalytically active due to loss of the critical active site residues. It may function not directly as a DNA methyltransferase but rather as a regulator of methylation at imprinted loci. It is required specifically for the establishment of genomic imprints but is dispensable for their propagation. It is essential for the de novo methylation of single-copy DNA sequences. The protein is well-express in testis, thymus, ovary, and heart. mDnmt3L, which belongs to the 5-cytosine methyltransferase family, contains 1 ADD-type zinc finger.
Other Names:
DNA (cytosine-5)-methyltransferase 3-like, Dnmt3l
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1062a was selected from the region of human Mouse Dnmt3L. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: Dnmt3l
Gene ID: 54427
Primary Accession: Q9CWR8
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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