Mouse Dnmt3L polyclonal, anti-human, mouse
€0.00
In stock
SKU
AC-AP1062a
Catalog Number: AC-AP1062a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2393
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2393
Applications: WB
Datasheet
Request Information
Background:
mDnmt3L (DNA methyltransferase 3L) does not appear to be catalytically active due to loss of the critical active site residues. It may function not directly as a DNA methyltransferase but rather as a regulator of methylation at imprinted loci. It is required specifically for the establishment of genomic imprints but is dispensable for their propagation. It is essential for the de novo methylation of single-copy DNA sequences. The protein is well-express in testis, thymus, ovary, and heart. mDnmt3L, which belongs to the 5-cytosine methyltransferase family, contains 1 ADD-type zinc finger.
Other Names:
DNA (cytosine-5)-methyltransferase 3-like, Dnmt3l
Target/Specificity:
This Mouse Dnmt3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-421 amino acids from mouse Dnmt3L.
Antigen Region:
389-421
Antigen Type: Synthetic Peptide
Gene Name: Dnmt3l
Gene ID: 54427
Primary Accession: Q9CWR8
NCBI Accession: NP_001075164.1;NP_062321.1
Other Accession: Q1LZ50
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
mDnmt3L (DNA methyltransferase 3L) does not appear to be catalytically active due to loss of the critical active site residues. It may function not directly as a DNA methyltransferase but rather as a regulator of methylation at imprinted loci. It is required specifically for the establishment of genomic imprints but is dispensable for their propagation. It is essential for the de novo methylation of single-copy DNA sequences. The protein is well-express in testis, thymus, ovary, and heart. mDnmt3L, which belongs to the 5-cytosine methyltransferase family, contains 1 ADD-type zinc finger.
Other Names:
DNA (cytosine-5)-methyltransferase 3-like, Dnmt3l
Target/Specificity:
This Mouse Dnmt3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-421 amino acids from mouse Dnmt3L.
Antigen Region:
389-421
Antigen Type: Synthetic Peptide
Gene Name: Dnmt3l
Gene ID: 54427
Primary Accession: Q9CWR8
NCBI Accession: NP_001075164.1;NP_062321.1
Other Accession: Q1LZ50
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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