Mouse Dyrk2 polyclonal (C-term), anti-human, mouse
€0.00
In stock
SKU
AC-AP14070B
Catalog Number: AC-AP14070B
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34467
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34467
Applications: WB, IHC-P
Datasheet
Request Information
Background:
Role in the regulation of cellular growth and/or development. Regulates TP53 by phosphorylation on Ser-46 to induce apoptosis in response to DNA damage, functioning downstream of ATM. Inactivates GYS1 by phosphorylation at Ser-641, and potentially also a second phosphorylation site, thus regulating glycogen synthesis. Phosphorylates EIF2B5 at Ser-544, enabling its subsequent phosphorylation and inhibition by GSK3, and may play a more general role in the priming of GSK3 substrates (By similarity).
Other Names:
Dual specificity tyrosine-phosphorylation-regulated kinase 2, Dyrk2 {ECO:0000312|MGI:MGI:1330301}
Target/Specificity:
This Mouse Dyrk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 521-549 amino acids from the C-terminal region of mouse Dyrk2.
Antigen Region:
521-549
Antigen Type: Synthetic Peptide
Gene Name: Dyrk2 {ECO:0000312|MGI:MGI:1330301}
Gene ID: 69181
Primary Accession: Q5U4C9
NCBI Accession: NP_001014412.1
Other Accession: NP_001014412.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Role in the regulation of cellular growth and/or development. Regulates TP53 by phosphorylation on Ser-46 to induce apoptosis in response to DNA damage, functioning downstream of ATM. Inactivates GYS1 by phosphorylation at Ser-641, and potentially also a second phosphorylation site, thus regulating glycogen synthesis. Phosphorylates EIF2B5 at Ser-544, enabling its subsequent phosphorylation and inhibition by GSK3, and may play a more general role in the priming of GSK3 substrates (By similarity).
Other Names:
Dual specificity tyrosine-phosphorylation-regulated kinase 2, Dyrk2 {ECO:0000312|MGI:MGI:1330301}
Target/Specificity:
This Mouse Dyrk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 521-549 amino acids from the C-terminal region of mouse Dyrk2.
Antigen Region:
521-549
Antigen Type: Synthetic Peptide
Gene Name: Dyrk2 {ECO:0000312|MGI:MGI:1330301}
Gene ID: 69181
Primary Accession: Q5U4C9
NCBI Accession: NP_001014412.1
Other Accession: NP_001014412.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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