Mouse Eif2ak1 Antibody (N-term) Blocking peptide

Background:
Mediates down-regulation of protein synthesis in response to various stress conditions by the phosphorylation of EIF2S1 at 'Ser-48' and 'Ser-51'. Protein synthesis is inhibited at the level of initiation.

Other Names:
Eukaryotic translation initiation factor 2-alpha kinase 1, Heme-controlled repressor, HCR, Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase, Heme-regulated inhibitor, Hemin-sensitive initiation factor 2-alpha kinase, Eif2ak1, Hri

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13913a was selected from the N-term region of Mouse Eif2ak1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: Eif2ak1 {ECO:0000312|MGI:MGI:1353448}

Gene ID: 15467
Primary Accession: Q9Z2R9
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.