Mouse Epha2 polyclonal (Center), anti-mouse
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In stock
SKU
AC-AP14619c
Catalog Number: AC-AP14619c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34764
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34764
Applications: WB
Datasheet
Request Information
Background:
Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A3, -A4 and -A5. Induces apoptosis in a TP53/p53-independent, caspase-8-dependent manner (By similarity). Plays an important role in angiogenesis and tumor neovascularization. The recruitement of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. May function in distinctive aspects of pattern formation and subsequently in development of several fetal tissues. May be involved in cell-cell interactions guiding early hindbrain development.
Other Names:
Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK, Tyrosine-protein kinase receptor MPK-5, Tyrosine-protein kinase receptor SEK-2, Epha2, Eck, Myk2, Sek2
Target/Specificity:
This Mouse Epha2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-323 amino acids from the Central region of mouse Epha2.
Antigen Region:
296-323
Antigen Type: Synthetic Peptide
Gene Name: Epha2
Gene ID: 13836
Primary Accession: Q03145
NCBI Accession: NP_034269.2
Other Accession: NP_034269.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A3, -A4 and -A5. Induces apoptosis in a TP53/p53-independent, caspase-8-dependent manner (By similarity). Plays an important role in angiogenesis and tumor neovascularization. The recruitement of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. May function in distinctive aspects of pattern formation and subsequently in development of several fetal tissues. May be involved in cell-cell interactions guiding early hindbrain development.
Other Names:
Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK, Tyrosine-protein kinase receptor MPK-5, Tyrosine-protein kinase receptor SEK-2, Epha2, Eck, Myk2, Sek2
Target/Specificity:
This Mouse Epha2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-323 amino acids from the Central region of mouse Epha2.
Antigen Region:
296-323
Antigen Type: Synthetic Peptide
Gene Name: Epha2
Gene ID: 13836
Primary Accession: Q03145
NCBI Accession: NP_034269.2
Other Accession: NP_034269.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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