Mouse Ern1 polyclonal (C-term), anti-mouse
€0.00
In stock
SKU
AC-AP14250b
Catalog Number: AC-AP14250b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34474
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34474
Applications: WB
Datasheet
Request Information
Background:
Ern1 senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
Other Names:
Serine/threonine-protein kinase/endoribonuclease IRE1, Endoplasmic reticulum-to-nucleus signaling 1, Inositol-requiring protein 1, Ire1-alpha, IRE1a, Serine/threonine-protein kinase, Endoribonuclease, 3126-, Ern1 {ECO:0000312|MGI:MGI:1930134}
Target/Specificity:
This Mouse Ern1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 827-855 amino acids from the C-terminal region of mouse Ern1.
Antigen Region:
827-855
Antigen Type: Synthetic Peptide
Gene Name: Ern1 {ECO:0000312|MGI:MGI:1930134}
Gene ID: 78943
Primary Accession: Q9EQY0
NCBI Accession: NP_076402.1
Other Accession: NP_076402.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Ern1 senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
Other Names:
Serine/threonine-protein kinase/endoribonuclease IRE1, Endoplasmic reticulum-to-nucleus signaling 1, Inositol-requiring protein 1, Ire1-alpha, IRE1a, Serine/threonine-protein kinase, Endoribonuclease, 3126-, Ern1 {ECO:0000312|MGI:MGI:1930134}
Target/Specificity:
This Mouse Ern1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 827-855 amino acids from the C-terminal region of mouse Ern1.
Antigen Region:
827-855
Antigen Type: Synthetic Peptide
Gene Name: Ern1 {ECO:0000312|MGI:MGI:1930134}
Gene ID: 78943
Primary Accession: Q9EQY0
NCBI Accession: NP_076402.1
Other Accession: NP_076402.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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