Mouse Hes1 polyclonal (Center), anti-mouse
€0.00
In stock
SKU
AC-AP20925a
Catalog Number: AC-AP20925a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB50935
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB50935
Applications: WB
Datasheet
Request Information
Background:
Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1 (By similarity). Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross- link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity).
Other Names:
Transcription factor HES-1, Hairy and enhancer of split 1, Hes1, Hes-1
Target/Specificity:
This Mouse Hes1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 102-137 amino acids from the Central region of Mouse Hes1.
Gene Name: Hes1
Gene ID: 15205
Primary Accession: P35428
Other Accession: Q04666; Q14469; Q3ZBG4; Q8AVU4; Q6IRB2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1 (By similarity). Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross- link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity).
Other Names:
Transcription factor HES-1, Hairy and enhancer of split 1, Hes1, Hes-1
Target/Specificity:
This Mouse Hes1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 102-137 amino acids from the Central region of Mouse Hes1.
Gene Name: Hes1
Gene ID: 15205
Primary Accession: P35428
Other Accession: Q04666; Q14469; Q3ZBG4; Q8AVU4; Q6IRB2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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