(Mouse) Hopx polyclonal (Center), anti-human, mouse, rat

(Mouse) Hopx polyclonal (Center), anti-human, mouse, rat

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In stock
SKU
AC-AP21373c
Catalog Number: AC-AP21373c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB51159
Applications: WB
Datasheet

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Background:
Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy.

Other Names:
Homeodomain-only protein, Homeobox-only protein, Odd homeobox protein 1, mOB1, Hopx, Hod, Hop, Ob1

Target/Specificity:
This Mouse Hopx antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 22-54 amino acids from the Central region of Mouse Hopx.

Antigen Region:
22-54

Gene Name: Hopx
Gene ID: 74318
Primary Accession: Q8R1H0
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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