Mouse Krt6a Blocking Peptide(Center)
€363.00
In stock
SKU
AC-BP19689c
Background:
Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation related keratins). Keratin 6 is found in hair follicles, neck squamous cell carcinomas, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation. There are at least six isoforms of human type II keratin 6 (K6), K6A being the most abundant representing about 77% of all forms found in epithelia.
Other Names:
Keratin, type II cytoskeletal 6A, Cytokeratin-6A, CK-6A, Keratin-6-alpha, mK6-alpha, Keratin-6A, K6A, Krt6a, Ker2, Krt2-6, Krt2-6a, Krt6
Target/Specificity:
The synthetic peptide sequence is selected from aa 227-240 of MOUSE Krt6a
Gene Name: Krt6a
Gene ID: 16687
Primary Accession: P50446
Other Accession: Q9Z331; NP_032502.3
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation related keratins). Keratin 6 is found in hair follicles, neck squamous cell carcinomas, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation. There are at least six isoforms of human type II keratin 6 (K6), K6A being the most abundant representing about 77% of all forms found in epithelia.
Other Names:
Keratin, type II cytoskeletal 6A, Cytokeratin-6A, CK-6A, Keratin-6-alpha, mK6-alpha, Keratin-6A, K6A, Krt6a, Ker2, Krt2-6, Krt2-6a, Krt6
Target/Specificity:
The synthetic peptide sequence is selected from aa 227-240 of MOUSE Krt6a
Gene Name: Krt6a
Gene ID: 16687
Primary Accession: P50446
Other Accession: Q9Z331; NP_032502.3
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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