Mouse Mapk8 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP14650c
Catalog Number: AC-AP14650c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB30269
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB30269
Applications: WB
Datasheet
Request Information
Background:
Mapk8 responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells. Phosphorylates heat shock factor protein 4 (HSF4) (By similarity).
Other Names:
Mitogen-activated protein kinase 8, MAP kinase 8, MAPK 8, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1, Mapk8, Jnk1, Prkm8
Target/Specificity:
This Mouse Mapk8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-268 amino acids from the Central region of mouse Mapk8.
Antigen Region:
239-268
Antigen Type: Synthetic Peptide
Primary Accession: Q91Y86 and P45983
NCBI Accession: NP_057909.1
Other Accession: Q8QHK8; P49185; NP_057909.1; P45983; Q91Y86
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Mapk8 responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells. Phosphorylates heat shock factor protein 4 (HSF4) (By similarity).
Other Names:
Mitogen-activated protein kinase 8, MAP kinase 8, MAPK 8, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1, Mapk8, Jnk1, Prkm8
Target/Specificity:
This Mouse Mapk8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-268 amino acids from the Central region of mouse Mapk8.
Antigen Region:
239-268
Antigen Type: Synthetic Peptide
Primary Accession: Q91Y86 and P45983
NCBI Accession: NP_057909.1
Other Accession: Q8QHK8; P49185; NP_057909.1; P45983; Q91Y86
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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