Mouse Mavs polyclonal (N-term), anti-mouse
€0.00
In stock
SKU
AC-AP20074a
Catalog Number: AC-AP20074a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB42373
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB42373
Applications: WB
Datasheet
Request Information
Background:
Required for innate immune defense against viruses. Acts downstream of DDX58 and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis (By similarity).
Other Names:
Mitochondrial antiviral-signaling protein, MAVS, CARD adapter inducing interferon beta, Cardif, Interferon beta promoter stimulator protein 1, IPS-1, Virus-induced-signaling adapter, VISA, Mavs, Ips1, Visa
Target/Specificity:
This Mouse Mavs antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse Mavs.
Antigen Region:
1-30
Antigen Type: Synthetic Peptide
Gene Name: Mavs {ECO:0000312|MGI:MGI:2444773}
Gene ID: 228607
Primary Accession: Q8VCF0
NCBI Accession: NP_001193314.1;NP_659137.1
Other Accession: NP_659137.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Required for innate immune defense against viruses. Acts downstream of DDX58 and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis (By similarity).
Other Names:
Mitochondrial antiviral-signaling protein, MAVS, CARD adapter inducing interferon beta, Cardif, Interferon beta promoter stimulator protein 1, IPS-1, Virus-induced-signaling adapter, VISA, Mavs, Ips1, Visa
Target/Specificity:
This Mouse Mavs antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse Mavs.
Antigen Region:
1-30
Antigen Type: Synthetic Peptide
Gene Name: Mavs {ECO:0000312|MGI:MGI:2444773}
Gene ID: 228607
Primary Accession: Q8VCF0
NCBI Accession: NP_001193314.1;NP_659137.1
Other Accession: NP_659137.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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