Mouse Myocd Blocking Peptide (C-term)

Background:
Smooth muscle cells (SM) and cardiac muscle cells- specific transcriptional factor which uses the canonical single or multiple CArG boxes DNA sequence. Acts as a cofactor of serum response factor (SRF) with the potential to modulate SRF-target genes. Plays a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage (myogenesis). Isoform 1 mediates the cardiac transcription factor MEF2C-dependent transcription. Isoform 1 and isoform 3 are more active than isoform 2 and isoform 4 in stimulating cardiac muscle promoters.

Other Names:
Myocardin, Basic SAP coiled-coil transcription activator 2, SRF cofactor protein, Myocd, Bsac2, Mycd, Srfcp

Target/Specificity:
The synthetic peptide sequence is selected from aa 743-757 of HUMAN Myocd

Gene Name: Myocd

Gene ID: 214384
Primary Accession: Q8VIM5
Other Accession: Q8R5I7; Q7YR76; Q8IZQ8
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.