Mouse Nkx3-1 polyclonal (Center), anti-mouse
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In stock
SKU
AC-AP19312c
Catalog Number: AC-AP19312c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB40187
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB40187
Applications: WB
Datasheet
Request Information
Background:
Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor (By similarity). Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to suppress growth and tumorigenicity of prostate carcinoma cells. Play a role in the formation of minor salivary glands (particularly palatine and lingual glands). Essential for appropriate differentiation and secretory function of the bulbourethral gland.
Other Names:
Homeobox protein Nkx-31, Homeobox protein NK-3 homolog A, Nkx3-1, Nkx-31, Nkx3a
Target/Specificity:
This Mouse Nkx3-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-86 amino acids from the Central region of mouse Nkx3-1.
Antigen Region:
3-1
Antigen Type: Synthetic Peptide
Gene Name: Nkx3-1 {ECO:0000312|MGI:MGI:97352}
Gene ID: 18095
Primary Accession: P97436
NCBI Accession: NP_035051.1
Other Accession: NP_035051.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor (By similarity). Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to suppress growth and tumorigenicity of prostate carcinoma cells. Play a role in the formation of minor salivary glands (particularly palatine and lingual glands). Essential for appropriate differentiation and secretory function of the bulbourethral gland.
Other Names:
Homeobox protein Nkx-31, Homeobox protein NK-3 homolog A, Nkx3-1, Nkx-31, Nkx3a
Target/Specificity:
This Mouse Nkx3-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-86 amino acids from the Central region of mouse Nkx3-1.
Antigen Region:
3-1
Antigen Type: Synthetic Peptide
Gene Name: Nkx3-1 {ECO:0000312|MGI:MGI:97352}
Gene ID: 18095
Primary Accession: P97436
NCBI Accession: NP_035051.1
Other Accession: NP_035051.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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