Mouse Nlk polyclonal (C-term), anti-human, mouse
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In stock
SKU
AC-AP13929b
Catalog Number: AC-AP13929b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34651
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34651
Applications: IHC-P, WB
Datasheet
Request Information
Background:
Role in cell fate determination, required for differentiation of bone marrow stromal cells. Acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. May suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP. Involved in TGFbeta-mediated mesoderm induction, acting downstream of MAP3K7/TAK1 to phosphorylate STAT3.
Other Names:
Serine/threonine-protein kinase NLK, Nemo-like kinase, Nlk {ECO:0000312|EMBL:AAC244991}
Target/Specificity:
This Mouse Nlk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 408-436 amino acids from the C-terminal region of mouse Nlk.
Antigen Region:
408-436
Antigen Type: Synthetic Peptide
Gene Name: Nlk {ECO:0000312|EMBL:AAC24499.1}
Gene ID: 18099
Primary Accession: O54949
NCBI Accession: NP_032728.3
Other Accession: D3ZSZ3; Q9UBE8; E1BMN8; NP_032728.3; XP_001472539.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Role in cell fate determination, required for differentiation of bone marrow stromal cells. Acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. May suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP. Involved in TGFbeta-mediated mesoderm induction, acting downstream of MAP3K7/TAK1 to phosphorylate STAT3.
Other Names:
Serine/threonine-protein kinase NLK, Nemo-like kinase, Nlk {ECO:0000312|EMBL:AAC244991}
Target/Specificity:
This Mouse Nlk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 408-436 amino acids from the C-terminal region of mouse Nlk.
Antigen Region:
408-436
Antigen Type: Synthetic Peptide
Gene Name: Nlk {ECO:0000312|EMBL:AAC24499.1}
Gene ID: 18099
Primary Accession: O54949
NCBI Accession: NP_032728.3
Other Accession: D3ZSZ3; Q9UBE8; E1BMN8; NP_032728.3; XP_001472539.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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