Mouse p27Kip1 polyclonal (C-term T197), anti-mouse

Mouse p27Kip1 polyclonal (C-term T197), anti-mouse

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In stock
SKU
AC-AP20325b
Catalog Number: AC-AP20325b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB42131
Applications: WB
Datasheet

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Background:
Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E-and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of cyclin D-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.

Other Names:
Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1, Cdkn1b

Target/Specificity:
This Mouse p27Kip1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-197 amino acids from the C-terminal region of mouse p27Kip1.

Antigen Region:
175-197

Antigen Type: Synthetic Peptide

Gene Name: Cdkn1b
Gene ID: 12576
Primary Accession: P46414
NCBI Accession: NP_034005.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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