Mouse Pak4 polyclonal (Center), anti-human, mouse
€0.00
In stock
SKU
AC-AP14453C
Catalog Number: AC-AP14453C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34853
Applications: WB, FC
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34853
Applications: WB, FC
Datasheet
Request Information
Background:
Pak4 activates the JNK pathway. Plays a role in the reorganization of the actin cytoskeleton and in the formation of filopodia. Phosphorylates and inactivates the protein phosphatase SSH1, leading to increased inhibitory phosphorylation of the actin binding/depolymerizing factor cofilin. Decreased cofilin activity may lead to stabilization of actin filaments. Phosphorylates ARHGEF2 (By similarity).
Other Names:
Serine/threonine-protein kinase PAK 4, p21-activated kinase 4, PAK-4, Pak4, Kiaa1142
Target/Specificity:
This Mouse Pak4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of mouse Pak4.
Antigen Region:
187-216
Antigen Type: Synthetic Peptide
Gene Name: Pak4
Gene ID: 70584
Primary Accession: Q8BTW9
NCBI Accession: NP_081746.1
Other Accession: O96013; NP_081746.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Pak4 activates the JNK pathway. Plays a role in the reorganization of the actin cytoskeleton and in the formation of filopodia. Phosphorylates and inactivates the protein phosphatase SSH1, leading to increased inhibitory phosphorylation of the actin binding/depolymerizing factor cofilin. Decreased cofilin activity may lead to stabilization of actin filaments. Phosphorylates ARHGEF2 (By similarity).
Other Names:
Serine/threonine-protein kinase PAK 4, p21-activated kinase 4, PAK-4, Pak4, Kiaa1142
Target/Specificity:
This Mouse Pak4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of mouse Pak4.
Antigen Region:
187-216
Antigen Type: Synthetic Peptide
Gene Name: Pak4
Gene ID: 70584
Primary Accession: Q8BTW9
NCBI Accession: NP_081746.1
Other Accession: O96013; NP_081746.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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