Mouse Prkci Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP14140a
Background:
Calcium-independent, phospholipid-dependent, serine-and threonine-specific kinase. May play a role in the secretory response to nutrients. Involved in cell polarization processes and the formation of epithelial tight junctions. Implicated in the activation of several signaling pathways including Ras, c-Src and NF-kappa-B pathways. Functions in both pro-and anti-apoptotic pathways. Functions in the RAC1/ERK signaling required for transformed growth. Plays a role in microtubule dynamics through interaction with RAB2A and GAPDH and recruitment to vesicular tubular clusters (VTCs) (By similarity).
Other Names:
Protein kinase C iota type, Atypical protein kinase C-lambda/iota, aPKC-lambda/iota, nPKC-iota, Prkci, Pkcl
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP14140a was selected from the N-term region of Mouse Prkci. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: Prkci
Gene ID: 18759
Primary Accession: Q62074
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Calcium-independent, phospholipid-dependent, serine-and threonine-specific kinase. May play a role in the secretory response to nutrients. Involved in cell polarization processes and the formation of epithelial tight junctions. Implicated in the activation of several signaling pathways including Ras, c-Src and NF-kappa-B pathways. Functions in both pro-and anti-apoptotic pathways. Functions in the RAC1/ERK signaling required for transformed growth. Plays a role in microtubule dynamics through interaction with RAB2A and GAPDH and recruitment to vesicular tubular clusters (VTCs) (By similarity).
Other Names:
Protein kinase C iota type, Atypical protein kinase C-lambda/iota, aPKC-lambda/iota, nPKC-iota, Prkci, Pkcl
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP14140a was selected from the N-term region of Mouse Prkci. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: Prkci
Gene ID: 18759
Primary Accession: Q62074
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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