Mouse Ptk2b polyclonal (Center), anti-human, mouse

Mouse Ptk2b polyclonal (Center), anti-human, mouse

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In stock
SKU
AC-AP14279C
Catalog Number: AC-AP14279C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34871
Applications: IHC-P, WB
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Background:
Involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. May represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage-gated potassium channel protein Kv1.2. Its activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity. Involved in osmotic stress-dependent SNCA 'Tyr-125' phosphorylation (By similarity).

Other Names:
Protein-tyrosine kinase 2-beta, Calcium-dependent tyrosine kinase, CADTK, Calcium-regulated non-receptor proline-rich tyrosine kinase, Cell adhesion kinase beta, CAK-beta, CAKB, Focal adhesion kinase 2, FADK 2, Proline-rich tyrosine kinase 2, Related adhesion focal tyrosine kinase, RAFTK, Ptk2b, Fak2, Pyk2, Raftk

Target/Specificity:
This Mouse Ptk2b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 672-701 amino acids from the Central region of mouse Ptk2b.

Antigen Region:
672-701

Antigen Type: Synthetic Peptide

Gene Name: Ptk2b
Gene ID: 19229
Primary Accession: Q9QVP9
NCBI Accession: NP_001155838.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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