Mouse Sike1 Blocking Peptide (N-term)
€363.00
In stock
SKU
AC-BP20223a
Background:
Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus-and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity).
Other Names:
Suppressor of IKBKE 1, Suppressor of IKK-epsilon, Sike1
Target/Specificity:
The synthetic peptide sequence is selected from aa 51-63 of MOUSE Sike1
Gene Name: Sike1
Gene ID: 66641
Primary Accession: Q9CPR7
Other Accession: Q5FWT9; NP_079955.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus-and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity).
Other Names:
Suppressor of IKBKE 1, Suppressor of IKK-epsilon, Sike1
Target/Specificity:
The synthetic peptide sequence is selected from aa 51-63 of MOUSE Sike1
Gene Name: Sike1
Gene ID: 66641
Primary Accession: Q9CPR7
Other Accession: Q5FWT9; NP_079955.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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