Mouse Sike1 polyclonal (N-term), anti-mouse
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In stock
SKU
AC-AP20223a
Catalog Number: AC-AP20223a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB42417
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB42417
Applications: WB
Datasheet
Request Information
Background:
Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus-and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity).
Other Names:
Suppressor of IKBKE 1, Suppressor of IKK-epsilon, Sike1
Target/Specificity:
This Mouse Sike1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-63 amino acids from the N-terminal region of mouse Sike1.
Antigen Region:
36-63
Antigen Type: Synthetic Peptide
Gene Name: Sike1
Gene ID: 66641
Primary Accession: Q9CPR7
NCBI Accession: NP_079955.1
Other Accession: Q5FWT9; NP_079955.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus-and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity).
Other Names:
Suppressor of IKBKE 1, Suppressor of IKK-epsilon, Sike1
Target/Specificity:
This Mouse Sike1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-63 amino acids from the N-terminal region of mouse Sike1.
Antigen Region:
36-63
Antigen Type: Synthetic Peptide
Gene Name: Sike1
Gene ID: 66641
Primary Accession: Q9CPR7
NCBI Accession: NP_079955.1
Other Accession: Q5FWT9; NP_079955.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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