Mouse Syk polyclonal (Center), anti-human
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In stock
SKU
AC-AP16152c
Catalog Number: AC-AP16152c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB35418
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB35418
Applications: WB
Datasheet
Request Information
Background:
Positive effector of BCR-stimulated responses. Couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-342 and Tyr-346. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion. Phosphorylates USP25 and regulates its intracellular levels (By similarity).
Other Names:
Tyrosine-protein kinase SYK, Spleen tyrosine kinase, Syk, ptk72, Sykb
Target/Specificity:
This Mouse Syk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the Central region of mouse Syk.
Antigen Region:
195-223
Antigen Type: Synthetic Peptide
Gene Name: Syk
Gene ID: 20963
Primary Accession: P48025
NCBI Accession: NP_001185906.1;NP_035648.2
Other Accession: Q64725; F1N9Y5; NP_035648.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Positive effector of BCR-stimulated responses. Couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-342 and Tyr-346. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion. Phosphorylates USP25 and regulates its intracellular levels (By similarity).
Other Names:
Tyrosine-protein kinase SYK, Spleen tyrosine kinase, Syk, ptk72, Sykb
Target/Specificity:
This Mouse Syk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the Central region of mouse Syk.
Antigen Region:
195-223
Antigen Type: Synthetic Peptide
Gene Name: Syk
Gene ID: 20963
Primary Accession: P48025
NCBI Accession: NP_001185906.1;NP_035648.2
Other Accession: Q64725; F1N9Y5; NP_035648.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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