Mouse Tbk1 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP17321a
Background:
Serine/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B. May function as an IKK kinase, playing an essential role in the transcription of a subset of a TNF-alpha-induced genes. Also mediates production of RANTES/CCL5 and interferon-beta/IFNB1. Has a pivotal role in the innate immune response. Phosphorylates and activates IRF3 and IRF7 and allows their nuclear localization. This leads to production of alpha/beta interferons and the development of a cellular antiviral state. It also seems to be a central factor in the induction of the antiviral interferon response.
Other Names:
Serine/threonine-protein kinase TBK1, T2K, TANK-binding kinase 1, Tbk1
Gene Name: Tbk1 {ECO:0000303|PubMed:10581243, ECO:0000312|MGI:MGI:1929658}
Gene ID: 56480
Primary Accession: Q9WUN2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Serine/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B. May function as an IKK kinase, playing an essential role in the transcription of a subset of a TNF-alpha-induced genes. Also mediates production of RANTES/CCL5 and interferon-beta/IFNB1. Has a pivotal role in the innate immune response. Phosphorylates and activates IRF3 and IRF7 and allows their nuclear localization. This leads to production of alpha/beta interferons and the development of a cellular antiviral state. It also seems to be a central factor in the induction of the antiviral interferon response.
Other Names:
Serine/threonine-protein kinase TBK1, T2K, TANK-binding kinase 1, Tbk1
Gene Name: Tbk1 {ECO:0000303|PubMed:10581243, ECO:0000312|MGI:MGI:1929658}
Gene ID: 56480
Primary Accession: Q9WUN2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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